Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CFD | P00746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30413093 | 0.87 | PTPN1 (0.41) | PTPN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL29272766 | 0.87 | PTPN1 (0.41) | PTPN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL286702 | 0.84 | KMT2A (0.48) | KDM4EKMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL31664051 | 0.82 | LMNA (0.47) | KDM4EKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL31454303 | 0.81 | GABRA1 (0.45) | PTPN1KMT2AMEN1TSHRBACE1 | |
| SCHEMBL965852 | 0.77 | KMT2A (0.51) | KDM4EKMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL31042998 | 0.77 | KMT2A (0.51) | KDM4EKMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL23703592 | 0.77 | KDM4E (0.43) | KDM4EKMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL5846257 | 0.77 | PTPN1 (0.42) | PTPN1KMT2AMEN1BACE1ALDH1A1 | |
| SCHEMBL2060569 | 0.76 | KDM4E (0.44) | KDM4EKMT2AMEN1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4673141-A1 | NBD1 MODULATORS AND METHODS OF USING THE SAME | Sionna Therapeutics Inc. (US) | 2026-01-07 | — | — | EP | disclosed |
| WO-2024182751-A1 | NBD1 MODULATORS AND METHODS OF USING THE SAME | SIONNA THERAPEUTICS INC. (US) | 2024-09-06 | — | — | WO | disclosed |