SCHEMBL31664051

SCHEMBL31664051

COC(=O)Cc1cccc(Br)c1OCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.47
HPGD P15428 1/20 0.47
THRB P10828 2/20 0.46
THRA P10827 1/20 0.46
KMT2A Q03164 5/20 0.45
MEN1 O00255 4/20 0.45
BCHE P06276 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
PTGER1 P34995 1/20 0.43
PTGER4 P35408 1/20 0.43
PTGER3 P43115 1/20 0.43
PTGER2 P43116 1/20 0.43
KDM4E B2RXH2 4/20 0.43
ALDH1A1 P00352 2/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
BLM P54132 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23219214 0.87 PRMT5 (0.47) LMNATHRBTHRAKMT2ASMN1; SMN2
SCHEMBL29853178 0.87 PRMT5 (0.47) LMNATHRBTHRAKMT2ASMN1; SMN2
SCHEMBL31664052 0.86 THRA (0.54) THRBTHRAPTGER1PTGER4PTGER3
SCHEMBL6036130 0.86 THRA (0.54) THRBTHRAPTGER1PTGER4PTGER3
SCHEMBL16050401 0.84 THRB (0.50) LMNAHPGDTHRBTHRAKMT2A
SCHEMBL31111007 0.82 PTPN1 (0.40) KMT2AMEN1KDM4EALDH1A1GAA
SCHEMBL286702 0.81 KMT2A (0.48) LMNAHPGDKMT2AMEN1SMN1; SMN2
SCHEMBL28006270 0.81 THRA (0.47) LMNAHPGDTHRBTHRABCHE
SCHEMBL8406694 0.79 LMNA (0.54) LMNAHPGDKMT2AMEN1SMN1; SMN2
SCHEMBL2988197 0.79 L3MBTL1 (0.56) LMNAHPGDTHRBKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4588927-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2025-07-23 EP disclosed