SCHEMBL965852

SCHEMBL965852

COC(=O)Cc1ccccc1Br

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.51
KDM4E B2RXH2 2/20 0.51
TSHR P16473 2/20 0.48
ALDH1A1 P00352 4/20 0.46
MEN1 O00255 1/20 0.46
CA12 O43570 2/20 0.45
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
CA9 Q16790 2/20 0.45
RIPK1 Q13546 1/20 0.45
TAAR1 Q96RJ0 1/20 0.44
MAPT P10636 2/20 0.44
GAA P10253 1/20 0.44
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
MAPK8 P45983 1/20 0.43
POLB P06746 1/20 0.43
PKM P14618 1/20 0.43
RAB9A P51151 1/20 0.43
TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31042998 1.00 KMT2A (0.51) KMT2AKDM4ETSHRALDH1A1MEN1
SCHEMBL5099244 0.86 KMT2A (0.47) KMT2AKDM4ETSHRALDH1A1MEN1
SCHEMBL1554320 0.86 KDM4E (0.53) KDM4ETSHRALDH1A1MAPTPOLB
SCHEMBL15056307 0.84 KDM4E (0.44) KMT2AKDM4ETSHRALDH1A1MEN1
SCHEMBL2060569 0.84 KDM4E (0.44) KMT2AKDM4ETSHRALDH1A1MEN1
SCHEMBL265432 0.82 CTBP2 (0.51) KMT2AKDM4ETSHRALDH1A1MEN1
SCHEMBL30522283 0.82 CTBP2 (0.51) KMT2AKDM4ETSHRALDH1A1MEN1
SCHEMBL5903219 0.82 KDM4E (0.43) KMT2AKDM4ETSHRALDH1A1MEN1
SCHEMBL286702 0.82 KMT2A (0.48) KMT2AKDM4ETSHRALDH1A1MEN1
SCHEMBL31284578 0.82 KDM4E (0.43) KMT2AKDM4ETSHRALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 562 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117756834-A Synthesis method of 2- (aminocarbonylmethyl) phenylboronic acid pinacol ester 大连双硼医药化工有限公司 2024-03-26 CN claimed
CN-116003682-B Acrylonitrile copolymer and preparation method and application thereof 山西钢科碳材料有限公司 2024-03-01 CN claimed
CN-116606400-A Wastewater treatment agent and preparation method thereof 山东诺尔生物科技有限公司 2023-08-18 CN claimed
CN-116003682-A Acrylonitrile copolymer and preparation method and application thereof 山西钢科碳材料有限公司 2023-04-25 CN claimed
CN-108047072-A A kind of synthetic method of C14H10Cl2NNaO2 深圳华中科技大学研究院 2018-05-18 CN claimed
CN-107793323-A A kind of synthetic method of Diclofenac methyl esters 华中科技大学 2018-03-13 CN claimed
CN-101659719-B Room-temperature self-repairing type thermoplastic polymer material and preparation method thereof UNIV SUN YAT SEN 2011-03-30 CN claimed
CN-101659719-A Room-temperature self-repairing type thermoplastic polymer material and preparation method thereof UNIV SUN YAT SEN 2010-03-03 CN claimed
WO-2001062803-A2 SUPPORTED CATALYSTS FOR USE IN ATOM TRANSFER RADICAL POLYMERIZATION AND CONTINUOUS PROCESSES FOR ATOM TRANSFER RADICAL POLYMERIZATION MCMASTER UNIVERSITY (CA) 2001-08-30 WO claimed
US-12606549-B2 Anticholinergic agents REZUBIO PHARMACEUTICALS CO., LTD (CN) 2026-04-21 US disclosed
US-20260078130-A1 NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF SIRONAX LTD (KY) 2026-03-19 US disclosed
EP-4692057-A1 NOVEL B0AT1 INHIBITOR Mitsubishi Tanabe Pharma Corporation (JP) 2026-02-11 EP disclosed
US-20260035335-A1 PI3K-ALPHA INHIBITORS AND METHODS OF USE THEREOF RELAY THERAPEUTICS INC (US) 2026-02-05 US disclosed
US-20260001849-A1 NOVEL B0AT1 INHIBITOR MITSUBISHI TANABE PHARMA CORPORATION (JP) 2026-01-01 US disclosed
WO-1991011999-A1 ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT MERCK & CO., INC. (US) 1991-08-22 WO disclosed
WO-1991012001-A1 ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT MERCK & CO., INC. (US) 1991-08-22 WO disclosed
WO-1991012002-A1 IMIDAZOLE ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT MERCK & CO., INC. (US) 1991-08-22 WO disclosed
US-4937374-A Process for preparing methyl 3-methoxy-2-(2-phenoxyphenyl)propenoalis IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-06-26 US disclosed
CN-1031840-A Benzofuran derivative and preparation method thereof TANABE SEIYAKU CO (JP) 1989-03-22 CN disclosed
US-4723031-A Processes for synthesizing substituted and unsubstituted aminoacetate esters CHEVRON RESEARCH COMPANY (US) 1988-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001849-A1 NOVEL B0AT1 INHIBITOR BCAT1, BCAT2, BHMT KMT2A 433/4885KDM4E 3501/4885TSHR 1492/4885
US-20260078130-A1 NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF NAMPT, NNMT, SARM1 KMT2A 2737/4885KDM4E 3382/4885TSHR 363/4885
US-12606549-B2 Anticholinergic agents CHRM1, CHRNA1, CHRND KMT2A 2414/4885KDM4E 3010/4885TSHR 54/4885
US-20260035335-A1 PI3K-ALPHA INHIBITORS AND METHODS OF USE THEREOF PIK3CD, PIK3CG, PIK3CB KMT2A 3086/4885KDM4E 1916/4885TSHR 3475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.