Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | TDO2 | P48775 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31111474 | 0.98 | CA12 (0.40) | CA12CA1CA2CA9PSIP1 | |
| SCHEMBL15579235 | 0.86 | CES2 (0.38) | CA12CA1CA2CA9PSIP1 | |
| SCHEMBL27540936 | 0.82 | PSIP1 (0.40) | CA12CA1CA2CA9PSIP1 | |
| SCHEMBL30636762 | 0.80 | PSIP1 (0.37) | CA12CA1CA2CA9PSIP1 | |
| SCHEMBL8607411 | 0.80 | TSHR (0.55) | CA12CA1CA2CA9TSHR | |
| SCHEMBL30536461 | 0.79 | APLNR (0.38) | MC4RCYP3A4IDO1TDO2CES2 | |
| SCHEMBL30536463 | 0.79 | APLNR (0.38) | MC4RCYP3A4IDO1TDO2CES2 | |
| SCHEMBL15923853 | 0.79 | CA2 (0.42) | CA12CA1CA2CA9TSHR | |
| SCHEMBL9860426 | 0.78 | CA12 (0.39) | CA12CA1CA2CA9PSIP1 | |
| SCHEMBL31190023 | 0.77 | CA1 (0.53) | CA12CA1CA2CA9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024227104-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING BRAF VIA UBIQUITIN PROTEOSOME PATHWAY | NURIX THERAPEUTICS, INC. (US) | 2024-10-31 | — | — | WO | disclosed |