Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 8/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | HK1 | P19367 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | VNN1 | O95497 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31119275 | 0.88 | CYP1A2 (0.45) | CYP1A2CYP3A4CLK4CYP2C19CYP2D6 | |
| SCHEMBL31119326 | 0.75 | CYP11B2 (0.44) | CYP1A2CYP3A4CLK4CYP2C19CYP2D6 | |
| SCHEMBL14243750 | 0.74 | CYP1A2 (0.55) | CYP1A2CYP3A4CLK4CYP2C19CYP2D6 | |
| SCHEMBL31119313 | 0.74 | CYP1A2 (0.41) | CYP1A2CYP3A4CLK4CYP2C19CYP2D6 | |
| SCHEMBL31119305 | 0.72 | SCD (0.45) | CYP1A2CYP3A4CLK4CYP2C19CYP2D6 | |
| SCHEMBL31119249 | 0.71 | POLB (0.45) | CYP1A2CYP3A4CLK4CYP2C19CYP2D6 | |
| SCHEMBL31119296 | 0.71 | DHPS (0.42) | CYP1A2CYP3A4CLK4CYP2C19CYP2D6 | |
| SCHEMBL31119271 | 0.70 | CYP1A2 (0.40) | CYP1A2CYP3A4CLK4CYP2C19CYP2D6 | |
| SCHEMBL417328 | 0.69 | CLK4 (0.52) | CYP1A2CYP3A4CLK4CYP2C19CYP2D6 | |
| SCHEMBL2128197 | 0.67 | MEN1 (0.62) | CYP1A2CYP3A4CLK4CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4683919-A1 | VANIN-1 INHIBITORS | Athos Therapeutics, Inc. (US) | 2026-01-28 | — | — | EP | disclosed |
| US-20250066353-A1 | VANIN-1 INHIBITORS | ATHOS THERAPEUTICS INC (US) | 2025-02-27 | — | — | US | disclosed |
| WO-2024196841-A1 | VANIN-1 INHIBITORS | ATHOS THERAPEUTICS, INC. (US) | 2024-09-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066353-A1 | VANIN-1 INHIBITORS | VCAM1, TMBIM6, VNN1 | CYP1A2 2868/4885CYP3A4 2422/4885CLK4 3285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.