Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.52 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.51 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.51 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12329232 | 0.90 | SOS1 (0.51) | SOS1GNAI3GNAO1GNAI1DRD2 | |
| SCHEMBL12420662 | 0.81 | MTNR1A (0.56) | GNAI3GNAO1GNAI1NPC1RAB9A | |
| SCHEMBL4034002 | 0.77 | CYP2C19 (0.60) | EPHX2SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7569582 | 0.76 | EPHX2 (0.64) | DRD2DRD3EPHX2SMN1; SMN2RAB9A | |
| SCHEMBL1808557 | 0.76 | SOS1 (0.82) | SOS1GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL8641864 | 0.74 | SMN1; SMN2 (0.63) | GNAI3GNAO1GNAI1EPHX2SMN1; SMN2 | |
| SCHEMBL31505725 | 0.74 | HTR2A (0.58) | EPHX2MTNR1AMTNR1BHTR2AHRH1 | |
| SCHEMBL17842262 | 0.74 | RAB9A (0.75) | EPHX2SMN1; SMN2NPC1PKMRAB9A | |
| SCHEMBL526330 | 0.74 | ALDH1A1 (0.73) | SMN1; SMN2ALDH1A1HTR2ACHRM1CHRM3 | |
| SCHEMBL20674229 | 0.74 | LMNA (0.73) | SOS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118666837-A | GPX4 protein degradation agent, preparation method and application thereof | 首都医科大学 | 2024-09-20 | — | — | CN | disclosed |