Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.42 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18666151 | 0.87 | MTNR1B (0.63) | MTNR1BTDP1ALDH1A1 | |
| SCHEMBL30567101 | 0.87 | MTNR1B (0.63) | MTNR1BTDP1ALDH1A1 | |
| SCHEMBL29660113 | 0.87 | ADRA2C (0.54) | MTNR1BTAOK1TDP1L3MBTL1ADRA2C | |
| SCHEMBL18666146 | 0.87 | ADRA2C (0.54) | MTNR1BTAOK1TDP1L3MBTL1ADRA2C | |
| SCHEMBL18666150 | 0.86 | MTNR1B (0.47) | MTNR1BBRAFTAOK1L3MBTL1ADRA2C | |
| SCHEMBL23099307 | 0.83 | KDM4E (0.46) | MTNR1BBRAFTAOK1L3MBTL1ADRA2C | |
| SCHEMBL18666199 | 0.82 | DEGS1 (0.49) | TAOK1TDP1L3MBTL1ADRA2CALDH1A1 | |
| SCHEMBL31120712 | 0.81 | MTNR1B (0.53) | MTNR1BL3MBTL1ALDH1A1 | |
| SCHEMBL18666157 | 0.81 | ALDH1A1 (0.48) | TAOK1L3MBTL1ADRA2CALDH1A1GAA | |
| SCHEMBL18666149 | 0.81 | ALDH1A1 (0.55) | MTNR1BTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459363-B | Fluorine substituted proliferation cell nuclear antigen inhibitor and preparation method and application thereof | 安徽贝克制药股份有限公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-118459363-A | Fluorine substituted proliferation cell nuclear antigen inhibitor and preparation method and application thereof | 安徽贝克制药股份有限公司 | 2024-08-09 | — | — | CN | disclosed |