Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | TEK | Q02763 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18666151 | 0.91 | MTNR1B (0.63) | MTNR1BKDM4ELMNAMAPTPOLB | |
| SCHEMBL30567101 | 0.91 | MTNR1B (0.63) | MTNR1BKDM4ELMNAMAPTPOLB | |
| SCHEMBL18666149 | 0.83 | ALDH1A1 (0.55) | MTNR1BKDM4ELMNAMAPTPOLB | |
| SCHEMBL31060099 | 0.83 | MTNR1B (0.48) | MTNR1BKDM4ELMNAMAPTPOLB | |
| SCHEMBL31522175 | 0.82 | MTNR1B (0.56) | MTNR1BKDM4EPOLBALDH1A1RECQL | |
| SCHEMBL31120716 | 0.81 | MTNR1B (0.47) | MTNR1BL3MBTL1ALDH1A1 | |
| SCHEMBL29660113 | 0.81 | ADRA2C (0.54) | MTNR1BLMNAL3MBTL1POLBKMT2A | |
| SCHEMBL18666146 | 0.81 | ADRA2C (0.54) | MTNR1BLMNAL3MBTL1POLBKMT2A | |
| SCHEMBL18666150 | 0.81 | MTNR1B (0.47) | MTNR1BKDM4EL3MBTL1MAPTALDH1A1 | |
| SCHEMBL25388461 | 0.80 | MTNR1B (0.62) | MTNR1BLMNAL3MBTL1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459363-B | Fluorine substituted proliferation cell nuclear antigen inhibitor and preparation method and application thereof | 安徽贝克制药股份有限公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-118459363-A | Fluorine substituted proliferation cell nuclear antigen inhibitor and preparation method and application thereof | 安徽贝克制药股份有限公司 | 2024-08-09 | — | — | CN | disclosed |