Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Zinc Ion SCHEMBL28517025 | 0.92 | ALDH1A1 (0.47) | — | |
| SCHEMBL28417831 | 0.92 | — | — | |
| SCHEMBL28345532 | 0.92 | ALDH1A1 (0.47) | — | |
| Potassium Ion SCHEMBL11792253 | 0.67 | CA1 (0.60) | — | |
| Potassium Ion SCHEMBL4362484 | 0.67 | — | — | |
| Potassium Ion SCHEMBL31530665 | 0.67 | CA1 (0.60) | — | |
| Metam SCHEMBL2458497 | 0.67 | CA1 (0.41) | — | |
| Potassium Ion SCHEMBL7266428 | 0.67 | — | — | |
| Metam SCHEMBL202666 | 0.67 | — | — | |
| Potassium Ion SCHEMBL7266434 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11241503-B2 | Oxadiazole linkers and use thereof | NEWBIO THERAPEUTICS, INC. (CN) | 2022-02-08 | — | — | US | disclosed |
| US-20210154320-A1 | OXADIAZOLE LINKERS AND USE THEREOF | NEWBIO THERAPEUTICS, INC. (CN) | 2021-05-27 | — | — | US | disclosed |
| WO-2019011078-A1 | OXADIAZOLE LINKERS AND USE THEREOF | NEWBIO THERAPEUTICS, INC. (CN) | 2019-01-17 | — | — | WO | disclosed |
| WO-2015106292-A1 | BCR-ABL TYROSINE-KINASE LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2015-07-16 | — | — | WO | disclosed |
| CN-102007133-B | 3-phenylpyrazolo [5,1-b ] thiazole compounds | EISAI R&D MAN CO LTD | 2013-06-12 | — | — | CN | disclosed |
| US-8431603-B2 | 3-phenylpyrazolo[5,1-b]thiazole compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2013-04-30 | — | — | US | disclosed |
| EP-2266990-B1 | 3-PHENYLPYRAZOLO[5,1-b]THIAZOLE COMPOUND | EISAI R&D MAN CO LTD (JP) | 2012-09-26 | — | — | EP | disclosed |
| EP-1869031-B1 | THIADIAZOLE SUBSTITUTED COUMARIN DERIVATIVES AND THEIR USE AS LEUKOTRIENE BIOSYNTHESIS INHIBITOR | MERCK CANADA INC (CA) | 2012-08-08 | — | — | EP | disclosed |
| CN-102007133-A | 3-phenylpyrazolo [5,1-b ] thiazole compounds | EISAI R&D MAN CO LTD | 2011-04-06 | — | — | CN | disclosed |
| EP-2266990-A1 | 3-PHENYLPYRAZOLOÝ5,1-b¨THIAZOLE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2010-12-29 | — | — | EP | disclosed |
| US-4861787-A | Nematicidal compositions | CIBA-GEIGY CORPORATION (US) | 1989-08-29 | — | — | US | disclosed |
| US-4727123-A | TRANSITION METAL COORDINATION COMPOUND AND COCATALYST | THE STANDARD OIL COMPANY (US) | 1988-02-23 | — | — | US | disclosed |
| US-4625002-A | Binuclear catalyst for the preparation of polyamide | THE STANDARD OIL COMPANY (US) | 1986-11-25 | — | — | US | disclosed |
| US-4603185-A | Catalytic process for the polymerization of acetylene | THE STANDARD OIL COMPANY (US) | 1986-07-29 | — | — | US | disclosed |
| EP-0155507-A2 | Azo dyes and liquid crystalline materials containing these dyes | BASF Aktiengesellschaft (DE) | 1985-09-25 | — | — | EP | disclosed |
| US-4482639-A | Catalysts for the polymerization of ethylene | THE STANDARD OIL COMPANY (US) | 1984-11-13 | — | — | US | disclosed |
| US-4144241-A | CEPHALOSPORIN MODIFIERS | SMITHKLINE CORPORATION (US) | 1979-03-13 | — | — | US | disclosed |
| US-4126682-A | 7-ACYL-3-(CARBOXYALKYL AND CARBAMOYLALKYL SUBSTITUTED OXADIAZOLYLTHIOMETHYL) CEPHALOSPORINS AND ANTIBACTERIAL COMPOSITIONS AND METHODS EMPLOYING THEM | SMITHKLINE CORPORATION (US) | 1978-11-21 | — | — | US | disclosed |
| US-4079134-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1978-03-14 | — | — | US | disclosed |
| US-4034092-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1977-07-05 | — | — | US | disclosed |