Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 3/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31137891 | 0.83 | SCN10A (0.47) | CYP11B2MAP4K4CYP11B1MKNK1MKNK2 | |
| SCHEMBL31137899 | 0.82 | IDO1 (0.46) | CYP11B2IDO1MAPK1CYP11B1MEN1 | |
| SCHEMBL14153055 | 0.80 | TAAR1 (0.55) | CYP11B2HPGDSCHEK2TAAR1ESR2 | |
| SCHEMBL31137905 | 0.79 | CYP11B1 (0.52) | CYP11B2CHEK2DYRK1AMAP4K4CYP11B1 | |
| SCHEMBL14153035 | 0.78 | HPGDS (0.70) | HPGDSCHEK2IDO1PIM1MAP4K4 | |
| SCHEMBL25544943 | 0.77 | HCAR2 (0.56) | CYP11B2HPGDSCHEK2IDO1DYRK1A | |
| SCHEMBL31475536 | 0.77 | HCAR2 (0.56) | CYP11B2HPGDSCHEK2IDO1DYRK1A | |
| SCHEMBL24844633 | 0.76 | HCAR2 (0.52) | KDM4EMEN1KMT2AKDM1A | |
| SCHEMBL24038372 | 0.75 | CYP11B2 (0.60) | CYP11B2IDO1TAAR1ESR2DYRK1A | |
| SCHEMBL14153034 | 0.75 | MAP4K4 (0.45) | CYP11B2HPGDSCHEK2TAAR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304591-B | Bridged ring steroid synthetase inhibitor and preparation method and application thereof | 广州中医药大学(广州中医药研究院) | 2024-10-01 | — | — | CN | disclosed |