SCHEMBL31138696

SCHEMBL31138696

Fc1cc(Br)cnc1-c1nc(C(F)(F)F)c[nH]1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.33
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31254780 0.78 AXL (0.35)
SCHEMBL25276213 0.75 NT5E (0.38)
SCHEMBL31255038 0.74 SDHB (0.37) CYP11B1CYP11B2
SCHEMBL30442598 0.73 SPR (0.39)
SCHEMBL25196015 0.73 SPR (0.39)
SCHEMBL31138387 0.70 HTT (0.42) SMN1; SMN2
SCHEMBL25792043 0.70 AMY1A (0.33) SMN1; SMN2
SCHEMBL4425449 0.69
SCHEMBL30442899 0.69 DGAT1 (0.40)
SCHEMBL10177266 0.69 DGAT1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024233605-A1 COMPOUNDS AND THEIR USE AGAINST CANCER TANGO THERAPEUTICS, INC. (US) 2024-11-14 WO disclosed