Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 9/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.50 |
| ▸ | RAF1 | P04049 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.47 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312442 | 0.89 | BACE1 (0.62) | ATMARCYP3A4MEN1KMT2A | |
| SCHEMBL311334 | 0.87 | EGFR (0.46) | KMT2AMAPTHPGDMAPK1POLH | |
| SCHEMBL311962 | 0.86 | EGFR (0.47) | MEN1KMT2AMAPTHPGDPOLH | |
| SCHEMBL10215485 | 0.86 | HPGD (0.59) | CYP3A4MEN1KMT2AMAPTHPGD | |
| SCHEMBL311828 | 0.84 | CYP2D6 (0.46) | CYP3A4MEN1KMT2AMAPTHPGD | |
| SCHEMBL312252 | 0.84 | AKR1B1 (0.46) | CYP3A4MEN1KMT2AMAPTHPGD | |
| SCHEMBL312410 | 0.84 | CYP3A4 (0.52) | CYP3A4MEN1KMT2AMAPTHPGD | |
| SCHEMBL312740 | 0.84 | AKR1B1 (0.57) | CYP3A4MEN1KMT2AHPGDMAPK1 | |
| SCHEMBL311888 | 0.81 | ATM (0.53) | ATMARCYP3A4MEN1KMT2A | |
| SCHEMBL313004 | 0.80 | ATM (0.52) | ATMARCYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093273-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-01-10 | — | — | US | disclosed |
| EP-2332527-A2 | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2011-06-15 | — | — | EP | disclosed |