Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10215485 | 0.91 | HPGD (0.59) | CYP3A4HPGDCYP2C19ALDH1A1TSHR | |
| SCHEMBL312252 | 0.91 | AKR1B1 (0.46) | CYP3A4HPGDCYP2C19ALDH1A1TSHR | |
| SCHEMBL312740 | 0.91 | AKR1B1 (0.57) | CYP3A4HPGDCYP2C19ALDH1A1TP53 | |
| SCHEMBL311334 | 0.86 | EGFR (0.46) | HPGDALDH1A1MAPTTP53SMN1; SMN2 | |
| SCHEMBL311402 | 0.84 | ATM (0.53) | CYP3A4HPGDCYP2C19ALDH1A1MAPT | |
| SCHEMBL312442 | 0.84 | BACE1 (0.62) | CYP3A4HPGDCYP2C19ALDH1A1TSHR | |
| SCHEMBL311828 | 0.83 | CYP2D6 (0.46) | CYP3A4HPGDCYP2C19ALDH1A1TSHR | |
| SCHEMBL311962 | 0.80 | EGFR (0.47) | HPGDALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL312219 | 0.80 | CYP3A4 (0.58) | CYP3A4HPGDCYP2C19ALDH1A1TSHR | |
| SCHEMBL311791 | 0.79 | HPGD (0.51) | CYP3A4HPGDCYP2C19ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093273-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-01-10 | — | — | US | disclosed |
| EP-2332527-A2 | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2011-06-15 | — | — | EP | disclosed |