Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | QPCT | Q16769 | 2/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312252 | 0.91 | AKR1B1 (0.46) | AKR1B1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10215485 | 0.91 | HPGD (0.59) | AKR1B1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL312410 | 0.91 | CYP3A4 (0.52) | AKR1B1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL312442 | 0.86 | BACE1 (0.62) | AKR1B1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL311334 | 0.84 | EGFR (0.46) | HPGDKMT2ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL311402 | 0.84 | ATM (0.53) | HPGDMEN1KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL311828 | 0.83 | CYP2D6 (0.46) | AKR1B1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL311962 | 0.80 | EGFR (0.47) | HPGDMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL312930 | 0.80 | AKR1B1 (0.57) | AKR1B1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL312117 | 0.79 | TNKS (0.55) | HPGDMEN1KMT2ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093273-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-01-10 | — | — | US | disclosed |
| EP-2332527-A2 | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2011-06-15 | — | — | EP | disclosed |