Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
| ▸ | ALPI | P09923 | 1/20 | 0.30 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31140499 | 0.86 | CDK8 (0.35) | — | |
| SCHEMBL31140480 | 0.79 | LMNA (0.41) | MAPTLMNASMN1; SMN2MEN1HPGD | |
| SCHEMBL9565873 | 0.76 | ALDH1A1 (0.43) | MAPTDHODHPOLBSMN1; SMN2MEN1 | |
| SCHEMBL31214299 | 0.76 | ALDH1A1 (0.43) | MAPTDHODHPOLBSMN1; SMN2MEN1 | |
| SCHEMBL6121546 | 0.68 | ALOX15 (0.37) | MAPTLMNAPOLBSMN1; SMN2ALPL | |
| SCHEMBL10364814 | 0.67 | MAPT (0.40) | MAPTDHODHLMNAPOLBMEN1 | |
| SCHEMBL15111107 | 0.66 | ALDH1A1 (0.39) | MAPTLMNAPOLBMEN1HPGD | |
| SCHEMBL30950328 | 0.65 | ASPH (0.39) | MAPTDHODHLMNAPOLBHPGD | |
| SCHEMBL12098246 | 0.64 | ALOX15 (0.48) | SMN1; SMN2 | |
| SCHEMBL4480620 | 0.64 | TAS2R14 (0.46) | LMNAHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118900841-A | Tricyclic compounds and uses thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2024-11-05 | — | — | CN | disclosed |