Sugi Predict

Sugi Predict / Compounds / SCHEMBL3114267

SCHEMBL3114267

SCHEMBL3114267

FCCc1ccc(N2CCNCC2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADRB1 P08588 7/20 0.53
▸ HTR3E A5X5Y0 3/20 0.53
▸ HTR3B O95264 3/20 0.53
▸ HTR3A P46098 3/20 0.53
▸ HTR3D Q70Z44 3/20 0.53
▸ HTR3C Q8WXA8 3/20 0.53
▸ SIGMAR1 Q99720 3/20 0.53
▸ ADRB2 P07550 1/20 0.48
▸ NCF1 P14598 1/20 0.48
▸ PLD1 Q13393 1/20 0.48
▸ LTA4H P09960 4/20 0.46
▸ ALDH1A1 P00352 2/20 0.46
▸ KDM4E B2RXH2 1/20 0.46
▸ LMNA P02545 1/20 0.46
▸ SIRT6 Q8N6T7 1/20 0.46
▸ CETP P11597 2/20 0.46
▸ USP2 O75604 1/20 0.44
▸ TSHR P16473 1/20 0.44
▸ HSD17B10 Q99714 1/20 0.44
▸ HTR6 P50406 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3123141 0.89 ADRB1 (0.50) ADRB1HTR3EHTR3BHTR3AHTR3D
Hydrochloric Acid SCHEMBL3118726 0.88 ADRB1 (0.49) ADRB1HTR3EHTR3BHTR3AHTR3D
SCHEMBL23120572 0.85 ADRB1 (0.53) ADRB1HTR3EHTR3BHTR3AHTR3D
SCHEMBL7272847 0.81 ADRB1 (0.53) ADRB1HTR3EHTR3BHTR3AHTR3D
SCHEMBL3637251 0.81 ADRB1 (0.58) ADRB1HTR3EHTR3BHTR3AHTR3D
SCHEMBL12298704 0.81 ADRB1 (0.57) ADRB1HTR3EHTR3BHTR3AHTR3D
SCHEMBL7433560 0.81 ADRB1 (0.49) ADRB1HTR3EHTR3BHTR3AHTR3D
SCHEMBL14724611 0.80 HTR7 (0.59) ADRB1HTR3EHTR3BHTR3AHTR3D
SCHEMBL5570604 0.79 ADRB1 (0.77) ADRB1HTR3EHTR3BHTR3AHTR3D
Hydrochloric Acid SCHEMBL27337206 0.79 ADRB1 (0.55) ADRB1HTR3EHTR3BHTR3AHTR3D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12324845-B2 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING, INC. (US) 2025-06-10 — — US disclosed
US-20250161500-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION LANTHEUS MEDICAL IMAGING, INC. (US) 2025-05-22 — — US disclosed
US-20220288243-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION LANTHEUS MEDICAL IMAGING, INC. (US) 2022-09-15 — — US disclosed
US-11241509-B2 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING, INC. (US) 2022-02-08 — — US disclosed
EP-2474525-B1 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING INC (US) 2020-04-15 — — EP disclosed
EP-2474523-B1 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING INC (US) 2020-04-08 — — EP disclosed
CN-110003079-A For making the ligand of imaging cardiac innervation 兰休斯医疗成像公司 2019-07-12 — — CN disclosed
CN-105622463-B For making the ligand of imaging cardiac innervation 兰休斯医疗成像公司 2019-02-22 — — CN disclosed
US-20180339070-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION LANTHEUS MEDICAL IMAGING, INC. (US) 2018-11-29 — — US disclosed
US-10010631-B2 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING, INC. (US) 2018-07-03 — — US disclosed
US-8491868-B2 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING, INC. (US) 2013-07-23 — — US disclosed
EP-2114873-B1 N-[3-BROMO-4-(3- [18F]FLUOROPROPOXY)-BENZYL]-GUANIDINE FOR IMAGING CARDIAC INNERVATION LANTHEUS MEDICAL IMAGING INC (US) 2013-02-20 — — EP disclosed
EP-2474526-A2 Ligands for imaging cardiac innervation Lantheus Medical Imaging, Inc. (US) 2012-07-11 — — EP disclosed
EP-2474525-A2 Ligands for imaging cardiac innervation Lantheus Medical Imaging, Inc. (US) 2012-07-11 — — EP disclosed
EP-2474524-A2 Ligands for imaging cardiac innervation Lantheus Medical Imaging, Inc. (US) 2012-07-11 — — EP disclosed
EP-2474523-A2 Ligands for imaging cardiac innervation Lantheus Medical Imaging, Inc. (US) 2012-07-11 — — EP disclosed
US-20100221182-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION CITIZENS BANK, N.A. 2010-09-02 — — US disclosed
CN-101687780-A ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING INC (US) 2010-03-31 — — CN disclosed
EP-2114873-A2 LIGANDS FOR IMAGING CARDIAC INNERVATION Lantheus Medical Imaging, Inc. (US) 2009-11-11 — — EP disclosed
WO-2008083056-A2 LIGANDS FOR IMAGING CARDIAC INNERVATION LANTHEUS MEDICAL IMAGING, INC. (US) 2008-07-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10010631-B2 Ligands for imaging cardiac innervation TNNT2, PNMT, TNNC1 ADRB1 7/4885HTR3E 379/4885HTR3B 250/4885
US-20100221182-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION TNNT2, PNMT, TNNC1 ADRB1 7/4885HTR3E 379/4885HTR3B 250/4885
US-20180339070-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION TNNT2, PNMT, TNNC1 ADRB1 7/4885HTR3E 379/4885HTR3B 250/4885
US-20220288243-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION TNNT2, PNMT, TNNC1 ADRB1 7/4885HTR3E 379/4885HTR3B 250/4885
US-11241509-B2 Ligands for imaging cardiac innervation TNNT2, PNMT, TNNC1 ADRB1 7/4885HTR3E 332/4885HTR3B 239/4885
US-20250161500-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION TNNT2, PNMT, TNNC1 ADRB1 7/4885HTR3E 379/4885HTR3B 250/4885
US-12324845-B2 Ligands for imaging cardiac innervation CHRNB4, RXFP4, RXFP3 ADRB1 35/4885HTR3E 538/4885HTR3B 320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.