Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.59 |
| ▸ | NCF1 | P14598 | 1/20 | 0.57 |
| ▸ | NCK1 | P16333 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8275784 | 1.00 | CYP1A2 (0.59) | CYP1A2NCF1NCK1BACE1ALDH1A1 | |
| SCHEMBL23229346 | 0.86 | NCF1 (0.59) | CYP1A2NCF1NCK1BACE1ALDH1A1 | |
| SCHEMBL8273778 | 0.79 | CYP1A2 (0.53) | CYP1A2NCK1BACE1ALDH1A1KDM4E | |
| SCHEMBL1500224 | 0.78 | NCF1 (0.55) | CYP1A2NCF1BACE1ALDH1A1KDM4E | |
| SCHEMBL3221495 | 0.78 | KDM4E (0.58) | NCF1NCK1BACE1ALDH1A1KDM4E | |
| SCHEMBL21864963 | 0.78 | NCF1 (0.55) | CYP1A2NCF1ALDH1A1APPTERT | |
| SCHEMBL14288335 | 0.77 | NCF1 (0.53) | NCF1APPTERTPSMB5NPC1 | |
| SCHEMBL9420844 | 0.76 | NCF1 (0.59) | CYP1A2NCF1ALDH1A1KDM4EGAA | |
| SCHEMBL30301243 | 0.76 | NCF1 (0.59) | CYP1A2NCF1ALDH1A1KDM4EGAA | |
| SCHEMBL28946505 | 0.74 | NCF1 (0.50) | NCF1ALDH1A1KDM4EGAACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12102631-B2 | Quinolylnitrones for the treatment and prevention of a cerebral stroke or ischaemia | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2024-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12102631-B2 | Quinolylnitrones for the treatment and prevention of a cerebral stroke or ischaemia | NLN, TXN2, TXN | CYP1A2 1858/4885NCF1 565/4885NCK1 1953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.