Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NCK1 | P16333 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8275784 | 0.86 | CYP1A2 (0.59) | NCF1CYP1A2ALDH1A1KDM4EGAA | |
| SCHEMBL31143623 | 0.86 | CYP1A2 (0.59) | NCF1CYP1A2ALDH1A1KDM4EGAA | |
| SCHEMBL31366067 | 0.78 | NCF1 (0.57) | NCF1CYP1A2ALDH1A1KDM4ETERT | |
| SCHEMBL22059366 | 0.75 | NQO2 (0.47) | NCF1CYP1A2ALDH1A1KDM4EGAA | |
| SCHEMBL4263734 | 0.74 | NCF1 (1.00) | NCF1CYP1A2ALDH1A1KDM4ELMNA | |
| SCHEMBL29946313 | 0.74 | NCF1 (1.00) | NCF1CYP1A2ALDH1A1KDM4ELMNA | |
| SCHEMBL31650826 | 0.74 | NCF1 (1.00) | NCF1CYP1A2ALDH1A1KDM4ELMNA | |
| SCHEMBL20008616 | 0.73 | TERT (0.80) | CYP1A2ALDH1A1KDM4EGAACYP2A6 | |
| SCHEMBL31261751 | 0.73 | CYP1A2 (1.00) | CYP1A2ALDH1A1KDM4ECYP2A6NQO2 | |
| SCHEMBL30081469 | 0.73 | CYP1A2 (1.00) | CYP1A2ALDH1A1KDM4ECYP2A6NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210107908-A1 | PHARMACEUTICAL COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2021-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210107908-A1 | PHARMACEUTICAL COMPOUNDS | MAPT, CYP3A5, SLC5A1 | NCF1 3920/4885CYP1A2 191/4885ALDH1A1 703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.