Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3105230 | 0.82 | NAPEPLD (0.48) | NAPEPLDPIK3CAMAPK1 | |
| SCHEMBL3100688 | 0.80 | PIK3CA (0.50) | NAPEPLDPIK3CAMAPK1 | |
| SCHEMBL3105942 | 0.80 | MAPK1 (0.51) | NAPEPLDPIK3CAMAPK1 | |
| SCHEMBL5485473 | 0.76 | POLB (0.43) | CNR2MAPK1PKM | |
| SCHEMBL3114918 | 0.75 | ALDH1A1 (0.42) | PIK3CACNR2PKMTSHR | |
| SCHEMBL3114617 | 0.74 | PIK3CA (0.48) | NAPEPLDPIK3CAMAPK1 | |
| SCHEMBL3117364 | 0.73 | PIK3CA (0.59) | NAPEPLDPIK3CA | |
| SCHEMBL3103448 | 0.73 | NAPEPLD (0.49) | NAPEPLDPIK3CAMAPK1 | |
| SCHEMBL3116657 | 0.72 | NAPEPLD (0.48) | NAPEPLDPIK3CAMAPK1 | |
| SCHEMBL28943227 | 0.72 | PIK3CA (0.53) | PIK3CATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100256132-A1 | IL-12 MODULATORY COMPOUNDS | SYNTA PHARMACEUTICALS CORPORATION (US) | 2010-10-07 | — | — | US | claimed |
| US-20060223996-A1 | IL-12 modulatory compounds | SYNTA PHARMACEUTICALS CORP. (US) | 2006-10-05 | — | — | US | claimed |
| US-8236795-B2 | IL-12 modulatory compounds | SYNTA PHARMACEUTICALS CORP. (US) | 2012-08-07 | — | — | US | disclosed |
| US-20100256132-A1 | IL-12 MODULATORY COMPOUNDS | SYNTA PHARMACEUTICALS CORPORATION (US) | 2010-10-07 | — | — | US | disclosed |
| US-7696202-B2 | IL-12 modulatory compounds | SYNTA PHARMACEUTICALS CORP. (US) | 2010-04-13 | — | — | US | disclosed |
| EP-1819341-A2 | IL-12 MODULATORY COMPOUNDS | Synta Pharmaceuticals Corporation (US) | 2007-08-22 | — | — | EP | disclosed |
| US-7226702-B2 | Solid polymer electrolyte and method of preparation | QUALLION LLC (US) | 2007-06-05 | — | — | US | disclosed |
| US-20060223996-A1 | IL-12 modulatory compounds | SYNTA PHARMACEUTICALS CORP. (US) | 2006-10-05 | — | — | US | disclosed |
| WO-2006053227-A2 | IL-12 MODULATORY COMPOUNDS | SYNTA PHARMACEUTICALS CORP. (US) | 2006-05-18 | — | — | WO | disclosed |
| US-20050019667-A1 | Solid polymer electrolyte and method of preparation | ENERGY, UNITED STATES DEPARTMENT OF | 2005-01-27 | — | — | US | disclosed |
| WO-2003083971-A1 | SOLID POLYMER ELECTROLYTE AND METHOD OF PREPARATION | QUALLION LLC (US) | 2003-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223996-A1 | IL-12 modulatory compounds | IL2, IL4, IFNG | NAPEPLD 1303/4885PIK3CA 2810/4885CNR2 330/4885 |
| US-20100256132-A1 | IL-12 MODULATORY COMPOUNDS | IL2, IL4, IFNG | NAPEPLD 1303/4885PIK3CA 2810/4885CNR2 330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.