SCHEMBL31153458

SCHEMBL31153458

COC(=O)c1ccc2c(n1)c(N(C)c1ccc(Cl)cc1)nn2C1CCOCC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TUBB4A P04350 2/20 0.38
▸ TUBB P07437 2/20 0.38
▸ TUBA3C P0DPH7 2/20 0.38
▸ TUBA1B P68363 2/20 0.38
▸ TUBA4A P68366 2/20 0.38
▸ TUBB4B P68371 2/20 0.38
▸ TUBB3 Q13509 2/20 0.38
▸ TUBB2A Q13885 2/20 0.38
▸ TUBB8 Q3ZCM7 2/20 0.38
▸ TUBA3E Q6PEY2 2/20 0.38
▸ TUBA1A Q71U36 2/20 0.38
▸ TUBA1C Q9BQE3 2/20 0.38
▸ TUBB6 Q9BUF5 2/20 0.38
▸ TUBB2B Q9BVA1 2/20 0.38
▸ TUBB1 Q9H4B7 2/20 0.38
▸ CREBBP Q92793 3/20 0.36
▸ BRD4 O60885 2/20 0.36
▸ KCNJ6 P48051 1/20 0.35
▸ KCNJ5 P48544 1/20 0.35
▸ KCNJ3 P48549 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31153553 0.90 CFTR (0.35) CREBBPBRD4KCNJ6KCNJ5KCNJ3
SCHEMBL31153407 0.89 TUBB4A (0.38) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL31153425 0.79 PDE4D (0.35) CREBBPNR3C1PDE4DKDM4C
SCHEMBL31153419 0.79 CREBBP (0.42) CREBBPBRD4NR3C1IRAK4PDE4D
SCHEMBL19657727 0.78 PTGER4 (0.40) CREBBPBRD4KCNJ6KCNJ5KCNJ3
SCHEMBL29704418 0.78 PTGER4 (0.40) CREBBPBRD4KCNJ6KCNJ5KCNJ3
SCHEMBL31153490 0.76 NR3C1 (0.34) CREBBPKCNJ6KCNJ5KCNJ3NR3C1
SCHEMBL26098592 0.73 PTGER4 (0.39) CREBBPBRD4PDE1APDE1BPDE1C
SCHEMBL23530017 0.70 PDE4D (0.41) PDE1APDE1BPDE1CIRAK4PTGER4
SCHEMBL29550149 0.70 PDE4D (0.41) PDE1APDE1BPDE1CIRAK4PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4698544-A1 COMPOUNDS AND USES THEREOF Foghorn Therapeutics Inc. (US) 2026-02-25 — — EP disclosed
WO-2024220946-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2024-10-24 — — WO disclosed
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