Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
| ▸ | PDE9A | O76083 | 4/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31153553 | 0.76 | CFTR (0.35) | NR3C1CNR1KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL31153458 | 0.76 | TUBB4A (0.38) | NR3C1KCNJ6KCNJ5KCNJ3CREBBP | |
| SCHEMBL31153419 | 0.73 | CREBBP (0.42) | NR3C1CREBBPPDE4DIRAK4 | |
| SCHEMBL31153425 | 0.66 | PDE4D (0.35) | NR3C1CREBBPPDE4DKDM4C | |
| SCHEMBL31153407 | 0.66 | TUBB4A (0.38) | NR3C1KCNJ6KCNJ5KCNJ3CREBBP | |
| SCHEMBL22822778 | 0.65 | CREBBP (0.48) | CNR1CNR2CREBBPSSTR4IRAK4 | |
| SCHEMBL22822410 | 0.63 | CREBBP (0.50) | PDE7ACREBBPSSTR4KDM4C | |
| SCHEMBL19657665 | 0.61 | CREBBP (0.48) | PDE7ACREBBP | |
| SCHEMBL19657320 | 0.59 | CREBBP (0.52) | PDE7ACREBBPKDM4C | |
| SCHEMBL19657312 | 0.58 | CREBBP (0.51) | PDE7ACREBBPPDE1APDE1BPDE1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4698544-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2026-02-25 | — | — | EP | disclosed |
| WO-2024220946-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2024-10-24 | — | — | WO | disclosed |