Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27225672 | 0.95 | PDK1 (0.48) | PDK1PDK2PDK3PDK4MEN1 | |
| SCHEMBL2629479 | 0.85 | CYP11B2 (0.53) | MEN1KMT2ASCD5CYP11B2ACACB | |
| SCHEMBL616090 | 0.85 | SCD5 (0.52) | MEN1KMT2ASCD5CYP11B2ACACB | |
| SCHEMBL28885244 | 0.84 | NPC1 (0.46) | PDK1PDK2PDK3PDK4MEN1 | |
| SCHEMBL27225612 | 0.83 | OPRD1 (0.44) | PDK1PDK2PDK3PDK4MEN1 | |
| SCHEMBL14716132 | 0.83 | ENPP2 (0.56) | MEN1KMT2ASCD5CYP11B2ACACB | |
| SCHEMBL2440617 | 0.83 | ENPP2 (0.56) | MEN1KMT2ASCD5CYP11B2ACACB | |
| SCHEMBL9977402 | 0.83 | HTR2C (0.53) | PDK1PDK2PDK3PDK4HTR2C | |
| SCHEMBL27225669 | 0.82 | OPRD1 (0.46) | PDK1PDK2PDK3PDK4MEN1 | |
| SCHEMBL27225644 | 0.82 | TACR1 (0.44) | PDK1PDK2PDK3PDK4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220399-A1 | PYRAZOLOTRIAZINECARBONITRILES USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-10-24 | — | — | WO | disclosed |