Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.36 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312297 | 0.88 | NLRP3 (0.42) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL312363 | 0.86 | CYP1A2 (0.37) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL311994 | 0.85 | KMT2A (0.46) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL312382 | 0.85 | CYP1A2 (0.39) | MEN1KMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL311421 | 0.84 | MEN1 (0.42) | NPC1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL312387 | 0.84 | CYP1A2 (0.38) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL312016 | 0.83 | HPGD (0.51) | MAPTMEN1KMT2AALDH1A1THRB | |
| SCHEMBL311043 | 0.82 | CYP1A2 (0.38) | MEN1KMT2AALDH1A1HPGDCYP1A2 | |
| SCHEMBL311753 | 0.82 | ALDH1A1 (0.43) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL312241 | 0.81 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093273-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-01-10 | — | — | US | disclosed |
| EP-2332527-A2 | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2011-06-15 | — | — | EP | disclosed |