Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312241 | 0.93 | ALDH1A1 (0.43) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL312016 | 0.92 | HPGD (0.51) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL311421 | 0.89 | MEN1 (0.42) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL312964 | 0.87 | MEN1 (0.45) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL312303 | 0.87 | TUBB4A (0.40) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL10215441 | 0.87 | KDM4E (0.45) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL311883 | 0.86 | GAA (0.46) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL312527 | 0.86 | MEN1 (0.46) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL311592 | 0.85 | NPC1 (0.38) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL311700 | 0.85 | ALDH1A1 (0.41) | KMT2AMEN1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093273-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-01-10 | — | — | US | disclosed |
| EP-2332527-A2 | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2011-06-15 | — | — | EP | disclosed |