Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311883 | 0.93 | GAA (0.46) | HPGDALDH1A1KMT2AMEN1THRB | |
| SCHEMBL311994 | 0.92 | KMT2A (0.46) | HPGDALDH1A1KMT2AMEN1THRB | |
| SCHEMBL311421 | 0.89 | MEN1 (0.42) | HPGDALDH1A1KMT2AMEN1THRB | |
| SCHEMBL10215441 | 0.87 | KDM4E (0.45) | HPGDALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL312303 | 0.87 | TUBB4A (0.40) | HPGDALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL312241 | 0.86 | ALDH1A1 (0.43) | HPGDALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL311592 | 0.83 | NPC1 (0.38) | HPGDALDH1A1KMT2AMEN1THRB | |
| SCHEMBL312363 | 0.83 | CYP1A2 (0.37) | HPGDALDH1A1KMT2AMEN1THRB | |
| SCHEMBL312228 | 0.81 | CYP1A2 (0.37) | HPGDALDH1A1KMT2AMEN1THRB | |
| SCHEMBL312297 | 0.81 | NLRP3 (0.42) | HPGDALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093273-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-01-10 | — | — | US | disclosed |
| EP-2332527-A2 | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2011-06-15 | — | — | EP | disclosed |