Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 5/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.36 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31170385 | 1.00 | SPR (0.44) | SPRGPR119RORCSSTR4JAK3 | |
| SCHEMBL31169977 | 0.85 | SETD7 (0.47) | SPRGPR119SMARCA2SMARCA4PBRM1 | |
| SCHEMBL2013279 | 0.77 | NOS1 (0.46) | GPR119KDM4E | |
| SCHEMBL31170653 | 0.75 | ABHD6 (0.43) | SPRGPR119RORCSETD7 | |
| SCHEMBL31170689 | 0.74 | ABHD6 (0.40) | SPRGPR119SSTR4SETD7 | |
| SCHEMBL31170003 | 0.73 | NOS1 (0.40) | KDM4E | |
| SCHEMBL31170091 | 0.73 | NOS1 (0.40) | KDM4E | |
| SCHEMBL26130115 | 0.72 | HPGD (0.50) | NR1H2 | |
| SCHEMBL3938157 | 0.71 | NR1H2 (0.49) | GPR119RORCNAMPTNR1H2 | |
| SCHEMBL1481922 | 0.71 | NR1H2 (0.49) | GPR119RORCNAMPTNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4712961-A2 | KRAS G12S AND G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| WO-2024238633-A2 | KRAS G12S AND G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2024-11-21 | — | — | WO | disclosed |