Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.43 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.41 |
| ▸ | SPR | P35270 | 3/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31169977 | 0.86 | SETD7 (0.47) | ABHD6DAGLASPRGPR119SETD7 | |
| SCHEMBL31170689 | 0.84 | ABHD6 (0.40) | ABHD6DAGLASPRGPR119SETD7 | |
| SCHEMBL31170462 | 0.80 | ABHD6 (0.42) | ABHD6DAGLAGPR119MEN1MAPT | |
| SCHEMBL31170385 | 0.75 | SPR (0.44) | SPRGPR119RORCSETD7 | |
| SCHEMBL31170139 | 0.75 | SPR (0.44) | SPRGPR119RORCSETD7 | |
| SCHEMBL31169853 | 0.73 | SCN9A (0.36) | — | |
| SCHEMBL20011906 | 0.72 | USP2 (0.42) | GPR119SETD7MEN1MAPTKMT2A | |
| SCHEMBL2013279 | 0.72 | NOS1 (0.46) | GPR119MEN1MAPTTSHRKMT2A | |
| SCHEMBL31257360 | 0.71 | F13A1 (0.38) | ABHD6GPR119SETD7MEN1MAPT | |
| SCHEMBL38662966 | 0.70 | USP30 (0.44) | GPR119USP30MEN1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4712961-A2 | KRAS G12S AND G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| WO-2024238633-A2 | KRAS G12S AND G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2024-11-21 | — | — | WO | disclosed |