Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3123596 | 0.93 | MAPT (0.48) | ALDH1A1LMNASMN1; SMN2KDM4EGAA | |
| SCHEMBL3117589 | 0.93 | L3MBTL1 (0.44) | ALDH1A1LMNASMN1; SMN2KDM4EGAA | |
| SCHEMBL3123548 | 0.90 | F7 (0.37) | ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL3129614 | 0.89 | PDE4B (0.40) | ALDH1A1LMNAHTTKDM4EMAPT | |
| SCHEMBL3129261 | 0.78 | AAK1 (0.39) | ALDH1A1LMNASMN1; SMN2TNFS1PR1 | |
| SCHEMBL3123524 | 0.78 | PDE4D (0.49) | ALDH1A1KDM4EGAAMAPTPDE4B | |
| SCHEMBL3131168 | 0.77 | SLC6A2 (0.40) | ALDH1A1LMNASMN1; SMN2TNFHTT | |
| SCHEMBL3122747 | 0.76 | PDE4B (0.47) | PDE4BL3MBTL1 | |
| SCHEMBL3200134 | 0.75 | SLC6A2 (0.43) | ALDH1A1LMNAKDM4EMAPTPDE4B | |
| SCHEMBL623386 | 0.75 | ALDH1A1 (0.48) | ALDH1A1LMNASMN1; SMN2TNFHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |