Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.38 |
| ▸ | CHKB | Q9Y259 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184593 | 0.95 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4MAPK1 | |
| SCHEMBL31185032 | 0.94 | MALT1 (0.44) | ALDH1A1SMN1; SMN2HPGDACHEMALT1 | |
| SCHEMBL31184917 | 0.93 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4MAPK1 | |
| SCHEMBL31184614 | 0.87 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4MAPK1 | |
| SCHEMBL31184945 | 0.83 | MCHR1 (0.38) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4MAPK1 | |
| SCHEMBL31184541 | 0.83 | JAK2 (0.38) | — | |
| SCHEMBL31185102 | 0.83 | POLB (0.44) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4MAPK1 | |
| SCHEMBL31184675 | 0.82 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4MAPK1 | |
| SCHEMBL31185053 | 0.82 | TP53 (0.40) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4MAPK1 | |
| SCHEMBL31184642 | 0.82 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |