Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | CHKB | Q9Y259 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | GNRHR | P30968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184418 | 0.93 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4MAPK1 | |
| SCHEMBL31184593 | 0.90 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4MAPK1 | |
| SCHEMBL31185032 | 0.90 | MALT1 (0.44) | ALDH1A1SMN1; SMN2HPGDMAPTACHE | |
| SCHEMBL31184949 | 0.89 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4MAPK1 | |
| SCHEMBL31184789 | 0.83 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4MAPK1 | |
| SCHEMBL31184614 | 0.82 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4MAPK1 | |
| SCHEMBL31185053 | 0.80 | TP53 (0.40) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4MAPK1 | |
| SCHEMBL31184508 | 0.80 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4MAPK1 | |
| SCHEMBL31184642 | 0.80 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4MAPK1 | |
| SCHEMBL31184541 | 0.80 | JAK2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |