Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | CALCA | P06881 | 1/20 | 0.32 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184615 | 0.84 | LMNA (0.31) | — | |
| SCHEMBL31184418 | 0.83 | ALDH1A1 (0.39) | — | |
| SCHEMBL31184593 | 0.83 | ALDH1A1 (0.39) | — | |
| SCHEMBL31185032 | 0.81 | MALT1 (0.44) | — | |
| SCHEMBL31184917 | 0.80 | ALDH1A1 (0.38) | — | |
| SCHEMBL31184692 | 0.77 | JAK2 (0.39) | JAK2 | |
| SCHEMBL31184568 | 0.76 | MAPK1 (0.32) | — | |
| SCHEMBL31184750 | 0.75 | BTK (0.34) | — | |
| SCHEMBL31184907 | 0.72 | JAK2 (0.40) | JAK2CALCRLCHRM4 | |
| SCHEMBL31184661 | 0.68 | ALDH1A1 (0.34) | JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |