Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 6/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | JAK1 | P23458 | 2/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184691 | 0.85 | JAK2 (0.45) | TYK2ABL1JAK1NPC1RAB9A | |
| SCHEMBL31184545 | 0.84 | KDM4E (0.43) | TYK2ABL1NPC1RAB9A | |
| SCHEMBL31184751 | 0.82 | MTNR1A (0.53) | — | |
| SCHEMBL31184632 | 0.81 | MAPK1 (0.46) | MAPK1BTKRAB9A | |
| SCHEMBL31184640 | 0.81 | POLB (0.45) | HPGDTYK2MAPK1NPC1RAB9A | |
| SCHEMBL31184972 | 0.81 | POLB (0.44) | HPGDTYK2MAPK1NPC1RAB9A | |
| SCHEMBL31184475 | 0.81 | POLB (0.49) | HPGDMAPK1 | |
| SCHEMBL31184673 | 0.81 | MALT1 (0.43) | TYK2ABL1NPC1RAB9A | |
| SCHEMBL31184819 | 0.80 | NPC1 (0.49) | HPGDABL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31185026 | 0.80 | KMT2A (0.48) | MAPK1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |