Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 2/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184797 | 0.84 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2LCKALDH1A1 | |
| SCHEMBL31184798 | 0.82 | LCK (0.39) | LCKAHRALDH1A1MEN1KMT2A | |
| SCHEMBL31184630 | 0.80 | HPGD (0.44) | NPC1RAB9ASMN1; SMN2ABL1HPGD | |
| SCHEMBL31185026 | 0.80 | KMT2A (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL31184979 | 0.79 | ALDH1A1 (0.46) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL31184422 | 0.78 | MAPK1 (0.40) | ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL31184529 | 0.77 | MAPK1 (0.49) | MEN1KMT2A | |
| SCHEMBL31184632 | 0.77 | MAPK1 (0.46) | RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL31184816 | 0.76 | MAPK1 (0.48) | MEN1KMT2A | |
| SCHEMBL31184452 | 0.76 | MAPK1 (0.51) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |