Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184545 | 0.86 | KDM4E (0.43) | KMT2ATSHRNPC1RAB9ATP53 | |
| SCHEMBL31184673 | 0.86 | MALT1 (0.43) | KMT2ATSHRNPC1RAB9ATP53 | |
| SCHEMBL31184630 | 0.85 | HPGD (0.44) | JAK1NPC1RAB9ATYK2SMN1; SMN2 | |
| SCHEMBL31184783 | 0.84 | MALT1 (0.54) | KMT2ATSHRTP53MEN1TYK2 | |
| SCHEMBL31184751 | 0.84 | MTNR1A (0.53) | KMT2ATSHRTP53MEN1MAPT | |
| SCHEMBL31184640 | 0.83 | POLB (0.45) | KMT2ATSHRNPC1RAB9AMAPT | |
| SCHEMBL31184475 | 0.83 | POLB (0.49) | KMT2ATP53MEN1MAPTPOLB | |
| SCHEMBL31184972 | 0.83 | POLB (0.44) | KMT2ATSHRNPC1RAB9AMAPT | |
| SCHEMBL31185026 | 0.83 | KMT2A (0.48) | KMT2ATSHRNPC1RAB9AHSD17B10 | |
| SCHEMBL31184979 | 0.82 | ALDH1A1 (0.46) | KMT2ATSHRNPC1RAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |