Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 13/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | CHKA | P35790 | 2/20 | 0.41 |
| ▸ | CHKB | Q9Y259 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184673 | 0.92 | MALT1 (0.43) | MALT1ABL1CHKACHKBKDM4E | |
| SCHEMBL31184902 | 0.85 | MALT1 (0.54) | MALT1TSHR | |
| SCHEMBL31184691 | 0.84 | JAK2 (0.45) | ABL1CHKAKDM4EMEN1TP53 | |
| SCHEMBL31184763 | 0.84 | EPHX2 (0.49) | MALT1GRM1MEN1TSHRKMT2A | |
| SCHEMBL31184499 | 0.83 | MALT1 (0.46) | MALT1CHKACHKBGRM1MEN1 | |
| SCHEMBL31184751 | 0.83 | MTNR1A (0.53) | CHKACHKBKDM4EMEN1TP53 | |
| SCHEMBL31184994 | 0.82 | GRM1 (0.44) | MALT1GRM1MEN1TSHRKMT2A | |
| SCHEMBL31184545 | 0.82 | KDM4E (0.43) | MALT1ABL1CHKACHKBKDM4E | |
| SCHEMBL31184972 | 0.81 | POLB (0.44) | MALT1CHKACHKBTSHRKMT2A | |
| SCHEMBL31184475 | 0.81 | POLB (0.49) | MALT1CHKACHKBMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |