Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.44 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184482 | 0.89 | TP53 (0.48) | FPR2UCHL1BRD4USP30KDM4E | |
| SCHEMBL121297 | 0.81 | NAMPT (0.50) | FPR2SCN9ANAMPTKCNH2SCN5A | |
| SCHEMBL24001751 | 0.79 | UCHL1 (0.45) | UCHL1PDK4DDB1CRBNPARP1 | |
| SCHEMBL20045450 | 0.79 | FPR2 (0.43) | FPR2NAMPTUSP30KDM4ERORC | |
| SCHEMBL14894232 | 0.78 | ABHD6 (0.43) | UCHL1USP30KDM4EPDK4DDB1 | |
| SCHEMBL20045447 | 0.78 | FPR2 (0.43) | FPR2SCN9AUSP30 | |
| SCHEMBL31749583 | 0.77 | FPR2 (0.48) | FPR2NAMPTUSP30DDB1CRBN | |
| SCHEMBL122428 | 0.77 | MGLL (0.47) | FPR2SCN9ABRD4NAMPTKCNH2 | |
| SCHEMBL24816737 | 0.77 | UCHL1 (0.41) | UCHL1BRD4DDB1CRBNPARP1 | |
| SCHEMBL20045536 | 0.76 | FPR2 (0.41) | FPR2SCN9ANAMPTUSP30KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |