Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184759 | 0.83 | MAPK1 (0.40) | HTR2AHTR2CHTR2BMAPK1 | |
| SCHEMBL31184760 | 0.83 | MAPK1 (0.40) | HTR2AHTR2CHTR2BMAPK1 | |
| SCHEMBL34472625 | 0.75 | L3MBTL1 (0.59) | TSHRCYP1A2CYP2C19L3MBTL1KCNH2 | |
| SCHEMBL31184453 | 0.74 | GRM1 (0.40) | MAPTGAAMEN1KMT2A | |
| SCHEMBL31184880 | 0.73 | MAPK1 (0.45) | HTR2AHTR2CHTR2BMAPK1ALDH1A1 | |
| SCHEMBL20596029 | 0.71 | ALOX15 (0.52) | TSHRL3MBTL1ALDH1A1MAPTGAA | |
| SCHEMBL31184577 | 0.70 | MAPK1 (0.46) | HTR2AHTR2CHTR2BMAPK1 | |
| Hydrochloric Acid SCHEMBL31184864 | 0.68 | HTR2B (0.48) | HTR2AHTR2CHTR2BMAPK1 | |
| SCHEMBL31184839 | 0.68 | IDH1 (0.39) | TSHRL3MBTL1HTR2AHTR2CHTR2B | |
| SCHEMBL23857271 | 0.68 | MAPT (0.56) | TSHRCYP1A2CYP2C19MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |