Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312016 | 0.93 | HPGD (0.51) | GAATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL312303 | 0.91 | TUBB4A (0.40) | GAATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10215441 | 0.91 | KDM4E (0.45) | GAATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL312241 | 0.91 | ALDH1A1 (0.43) | GAATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL311421 | 0.89 | MEN1 (0.42) | GAATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL311994 | 0.86 | KMT2A (0.46) | ALDH1A1HPGDKDM4EHSD17B10MEN1 | |
| SCHEMBL311043 | 0.85 | CYP1A2 (0.38) | GAATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL312382 | 0.84 | CYP1A2 (0.39) | GAAALOX5ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL312363 | 0.83 | CYP1A2 (0.37) | GAATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL312167 | 0.83 | CYP1A2 (0.38) | GAAALDH1A1HPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093273-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-01-10 | — | — | US | disclosed |
| EP-2332527-A2 | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2011-06-15 | — | — | EP | disclosed |