Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311236 | 0.88 | PLA2G7 (0.45) | CYP1A2CYP2C9CYP2C19HSD17B10HPGD | |
| SCHEMBL312228 | 0.86 | CYP1A2 (0.37) | CYP1A2CYP2C9CYP2C19SMN1; SMN2AKR1B1 | |
| SCHEMBL311889 | 0.85 | CYP1A2 (0.40) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HSD17B10 | |
| SCHEMBL312241 | 0.85 | ALDH1A1 (0.43) | CYP1A2CYP2C9CYP2C19SMN1; SMN2AKR1B1 | |
| SCHEMBL311496 | 0.84 | HPGD (0.41) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HSD17B10 | |
| SCHEMBL311043 | 0.84 | CYP1A2 (0.38) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HSD17B10 | |
| SCHEMBL312303 | 0.83 | TUBB4A (0.40) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HSD17B10 | |
| SCHEMBL311883 | 0.83 | GAA (0.46) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HSD17B10 | |
| SCHEMBL10215441 | 0.81 | KDM4E (0.45) | SMN1; SMN2HSD17B10HPGDKDM4EMEN1 | |
| SCHEMBL311994 | 0.81 | KMT2A (0.46) | CYP1A2CYP2C9CYP2C19SMN1; SMN2AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093273-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-01-10 | — | — | US | disclosed |
| EP-2332527-A2 | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2011-06-15 | — | — | EP | disclosed |