SCHEMBL31191376

SCHEMBL31191376

CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 6/20 0.47
▸ NTSR1 P30989 5/20 0.46
▸ NTSR2 O95665 3/20 0.46
▸ SORT1 Q99523 3/20 0.46
▸ APLNR P35414 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31191247 0.95 OPRD1 (0.48) OPRD1NTSR1NTSR2SORT1
SCHEMBL31191293 0.95 OPRD1 (0.49) OPRD1NTSR1NTSR2SORT1
SCHEMBL29569246 0.90 NTSR1 (0.44) OPRD1NTSR1NTSR2SORT1APLNR
SCHEMBL30933084 0.88 NTSR1 (0.49) OPRD1NTSR1NTSR2SORT1APLNR
SCHEMBL29800900 0.87 NTSR1 (0.48) OPRD1NTSR1NTSR2SORT1
SCHEMBL29399877 0.86 NTSR1 (0.46) OPRD1NTSR1NTSR2SORT1APLNR
SCHEMBL21312656 0.86 APLNR (0.45) OPRD1NTSR1APLNR
SCHEMBL31067246 0.86 PTPN1 (0.43) OPRD1NTSR1NTSR2APLNR
SCHEMBL29800934 0.85 PTPN1 (0.42) OPRD1NTSR1APLNR
SCHEMBL29421978 0.85 APLNR (0.51) OPRD1NTSR1NTSR2APLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166266-B Anti-mesothelin constructs and uses thereof 上海偌妥生物科技有限公司 2025-06-24 — — CN disclosed
US-12215130-B2 Cytokine-albumin binding moiety fusion proteins and uses thereof ANWITA BIOSCIENCES, INC. (US) 2025-02-04 — — US disclosed
US-12091438-B2 Anti-mesothelin constructs and uses thereof ANWITA BIOSCIENCES, INC. (US) 2024-09-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12091438-B2 Anti-mesothelin constructs and uses thereof IL15, IL15RA, EPS15 OPRD1 4260/4885NTSR1 518/4885NTSR2 772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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