Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT14 | O95848 | 2/20 | 0.64 |
| ▸ | NUDT5 | Q9UKK9 | 2/20 | 0.64 |
| ▸ | PIK3CD | O00329 | 10/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.54 |
| ▸ | PIK3CB | P42338 | 10/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 10/20 | 0.54 |
| ▸ | PRKDC | P78527 | 10/20 | 0.54 |
| ▸ | SRC | P12931 | 8/20 | 0.53 |
| ▸ | ABL1 | P00519 | 7/20 | 0.53 |
| ▸ | EGFR | P00533 | 7/20 | 0.53 |
| ▸ | HCK | P08631 | 7/20 | 0.53 |
| ▸ | MTOR | P42345 | 7/20 | 0.53 |
| ▸ | EPHB4 | P54760 | 7/20 | 0.53 |
| ▸ | KDR | P35968 | 7/20 | 0.53 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 5/20 | 0.45 |
| ▸ | LCK | P06239 | 2/20 | 0.44 |
| ▸ | TEK | Q02763 | 2/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL130622 | 0.86 | PIK3CB (0.58) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL16285724 | 0.85 | NUDT14 (0.70) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL22692814 | 0.82 | NUDT14 (0.72) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL12282 | 0.80 | PIK3CD (0.59) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL22692820 | 0.79 | NUDT14 (0.75) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL130529 | 0.78 | NUDT14 (1.00) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL23917226 | 0.76 | NUDT14 (0.55) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL22243276 | 0.74 | NUDT14 (0.67) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL21436351 | 0.74 | PIK3CB (0.53) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL31165915 | 0.74 | PIK3CB (0.53) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4719385-A2 | 1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINES AS ANTI-INFECTIOUS AGENTS | University of Vermont and State Agricultural College (US) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024249380-A2 | 1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINES AS ANTI-INFECTIOUS AGENTS | UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 2024-12-05 | — | — | WO | disclosed |