Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT14 | O95848 | 2/20 | 0.75 |
| ▸ | NUDT5 | Q9UKK9 | 2/20 | 0.75 |
| ▸ | PIK3CD | O00329 | 11/20 | 0.63 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.63 |
| ▸ | PIK3CB | P42338 | 11/20 | 0.63 |
| ▸ | PIK3CG | P48736 | 11/20 | 0.63 |
| ▸ | PRKDC | P78527 | 11/20 | 0.63 |
| ▸ | SRC | P12931 | 10/20 | 0.60 |
| ▸ | ABL1 | P00519 | 9/20 | 0.60 |
| ▸ | EGFR | P00533 | 9/20 | 0.60 |
| ▸ | HCK | P08631 | 9/20 | 0.60 |
| ▸ | MTOR | P42345 | 9/20 | 0.60 |
| ▸ | EPHB4 | P54760 | 9/20 | 0.60 |
| ▸ | KDR | P35968 | 9/20 | 0.60 |
| ▸ | FYN | P06241 | 2/20 | 0.58 |
| ▸ | BTK | Q06187 | 5/20 | 0.58 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.53 |
| ▸ | LCK | P06239 | 2/20 | 0.50 |
| ▸ | LYN | P07948 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22692814 | 0.87 | NUDT14 (0.72) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL22243276 | 0.86 | NUDT14 (0.67) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL130529 | 0.86 | NUDT14 (1.00) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL23917243 | 0.82 | KDM4E (0.69) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL24041271 | 0.81 | BTK (0.76) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL130752 | 0.80 | NUDT14 (0.74) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL31194646 | 0.79 | NUDT14 (0.64) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL24196897 | 0.79 | BTK (0.65) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL30415747 | 0.79 | BTK (0.65) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL409367 | 0.79 | PIK3CD (0.82) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844038-B2 | 1,2-dithiolane compounds useful in neuroprotection, autoimmune and cancer diseases and conditions | SABILA BIOSCIENCES LLC (US) | 2020-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10844038-B2 | 1,2-dithiolane compounds useful in neuroprotection, autoimmune and cancer diseases and conditions | BTK, FYN, YES1 | NUDT14 4860/4885NUDT5 4862/4885PIK3CD 191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.