Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 8/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31196433 | 0.85 | HPGD (0.40) | HPGDCNR2ACACB | |
| SCHEMBL22247294 | 0.80 | KMO (0.40) | CNR2ACACBMEN1KMT2AKMO | |
| SCHEMBL31196319 | 0.76 | KMT2A (0.42) | HPGDLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL31196334 | 0.71 | PARP10 (0.41) | CNR2KMO | |
| SCHEMBL2705546 | 0.71 | FFAR4 (0.39) | CNR2ACACBMEN1KMT2AKMO | |
| SCHEMBL25194853 | 0.69 | LMNA (0.65) | LMNASMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL2704510 | 0.69 | SLC6A4 (0.35) | CNR2ACACB | |
| SCHEMBL31038214 | 0.69 | LMNA (0.65) | LMNASMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL31196542 | 0.68 | ALDH1A1 (0.45) | HPGDSMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL15114932 | 0.67 | CDK2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709716-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233554-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2024-11-14 | — | — | WO | disclosed |