Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 3/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.32 |
| ▸ | MERTK | Q12866 | 2/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.31 |
| ▸ | CCR4 | P51679 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 2/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3128313 | 0.81 | KDM1A (0.33) | MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL3131475 | 0.77 | SPAST (0.33) | MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL3130113 | 0.75 | HTR6 (0.34) | MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL3131793 | 0.74 | CHEK1 (0.35) | KMT2AALDH1A1 | |
| SCHEMBL3131842 | 0.66 | TAAR1 (0.35) | KMT2AALDH1A1 | |
| SCHEMBL3129018 | 0.64 | TAAR1 (0.35) | ALDH1A1 | |
| SCHEMBL3124869 | 0.63 | TSHR (0.34) | MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL7662487 | 0.60 | PAK1 (0.60) | FLT3TYRO3MERTKAXLADORA3 | |
| SCHEMBL2044430 | 0.60 | SLC6A2 (0.39) | MEN1KMT2AJAK2ALDH1A1JAK1 | |
| SCHEMBL1445582 | 0.60 | HSD17B10 (0.40) | MEN1KMT2AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100204187-A1 | Purine Derivatives | PALAU PHARMA, S.A. (ES) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204187-A1 | Purine Derivatives | JAK3, JAK1, JAK2 | FLT3 51/4885TYRO3 254/4885MERTK 554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.