Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPAST | Q9UBP0 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.32 |
| ▸ | PRKCG | P05129 | 2/20 | 0.32 |
| ▸ | PRKCB | P05771 | 2/20 | 0.32 |
| ▸ | PRKCA | P17252 | 2/20 | 0.32 |
| ▸ | PRKACA | P17612 | 2/20 | 0.32 |
| ▸ | PRKACG | P22612 | 2/20 | 0.32 |
| ▸ | PRKACB | P22694 | 2/20 | 0.32 |
| ▸ | PRKCH | P24723 | 2/20 | 0.32 |
| ▸ | PRKCI | P41743 | 2/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.32 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2044430 | 0.84 | SLC6A2 (0.39) | SPASTPRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL3130113 | 0.82 | HTR6 (0.34) | SMN1; SMN2TP53CYP3A4CYP2D6HSD17B10 | |
| SCHEMBL3120089 | 0.77 | FLT3 (0.32) | TP53MEN1KMT2AALDH1A1 | |
| SCHEMBL3128313 | 0.76 | KDM1A (0.33) | SMN1; SMN2TP53HSD17B10MEN1TSHR | |
| SCHEMBL5132646 | 0.75 | PKM (0.37) | SPASTPRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL3131793 | 0.74 | CHEK1 (0.35) | SMN1; SMN2HSD17B10ALOX15TSHRMAPK1 | |
| SCHEMBL28284328 | 0.68 | PRKD3 (0.43) | PRKD3PRKCGPRKCBPRKCAPRKACA | |
| SCHEMBL18009416 | 0.67 | HTR2C (0.44) | PRKD3PRKCGPRKCBPRKCAPRKACA | |
| SCHEMBL3131842 | 0.66 | TAAR1 (0.35) | SMN1; SMN2HSD17B10MAPK1KMT2AHTT | |
| SCHEMBL3129018 | 0.66 | TAAR1 (0.35) | SMN1; SMN2HSD17B10HTTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100204187-A1 | Purine Derivatives | PALAU PHARMA, S.A. (ES) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204187-A1 | Purine Derivatives | JAK3, JAK1, JAK2 | SPAST 4209/4885PRKD3 28/4885PRKCG 626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.