Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MITF | O75030 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3120970 | 0.92 | RAB9A (0.39) | DGAT2SMN1; SMN2NPC1RAB9ACREBBP | |
| SCHEMBL3131347 | 0.89 | PDE4A (0.49) | SMN1; SMN2NPC1RAB9AALDH1A1GAA | |
| SCHEMBL3125816 | 0.75 | LMNA (0.48) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL3123717 | 0.73 | TSHR (0.47) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL3117724 | 0.73 | DGAT2 (0.41) | DGAT2SMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL3131001 | 0.70 | PDE4A (0.55) | PDE4A | |
| SCHEMBL3120585 | 0.69 | F7 (0.42) | RAB9AMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL2902041 | 0.68 | PDE4A (0.46) | PDE4A | |
| SCHEMBL2908318 | 0.68 | PDE4A (0.46) | PDE4A | |
| SCHEMBL2902818 | 0.68 | PDE4A (0.46) | PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |