SCHEMBL1479983

SCHEMBL1479983

CC(C)(C)c1cc2c(cc1-c1ccc(Cl)cc1)Cc1cc(-c3ccc(Cl)cc3)c(C(C)(C)C)cc1-2

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 1/20 0.37
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
AHR P35869 1/20 0.35
JAK2 O60674 1/20 0.35
NTRK1 P04629 1/20 0.35
MET P08581 1/20 0.35
FGFR1 P11362 1/20 0.35
PRKACA P17612 1/20 0.35
KDR P35968 1/20 0.35
MAP2K2 P36507 1/20 0.35
FLT3 P36888 1/20 0.35
GSK3B P49841 1/20 0.35
MAP2K1 Q02750 1/20 0.35
MST1R Q04912 1/20 0.35
NTRK3 Q16288 1/20 0.35
NTRK2 Q16620 1/20 0.35
CAMK1D Q8IU85 1/20 0.35
CNR1 P21554 3/20 0.33
CNR2 P34972 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4954208 0.84 ESR1 (0.36) ESR1ESR2MAPTMETAP1PTGS2
SCHEMBL312040 0.84 KIF11 (0.41) TDP2MAPTKMT2AGCGR
SCHEMBL16411267 0.83 TDP2 (0.30) TDP2
SCHEMBL1480432 0.83 TDP2 (0.38) TDP2ESR1ESR2NTRK2MAPT
SCHEMBL1480584 0.83 PTGS2 (0.38) ESR1ESR2PGRMAPTGCGR
SCHEMBL312383 0.82 BACE1 (0.34) TDP2ESR1ESR2MAPTMEN1
SCHEMBL1479601 0.81 TDP2 (0.43) TDP2ESR1ESR2
SCHEMBL1482711 0.80 ABL1 (0.41) MAPTGAAMETAP1
SCHEMBL1480179 0.79 PGR (0.38) PGRMAPTMETAP1
SCHEMBL16411265 0.77 AHR (0.36) AHRCNR1CNR2TRPV1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2829555-B1 METHOD FOR PRODUCING OLEFIN POLYMER MITSUI CHEMICALS INC (JP) 2018-05-16 EP disclosed
US-9315602-B2 Method for producing olefin polymer MITSUI CHEMICALS, INC. (JP) 2016-04-19 US disclosed
US-20150045523-A1 METHOD FOR PRODUCING OLEFIN POLYMER MITSUI CHEMICALS, INC. (JP) 2015-02-12 US disclosed
EP-2829555-A1 METHOD FOR PRODUCING OLEFIN POLYMER Mitsui Chemicals, Inc. (JP) 2015-01-28 EP disclosed
US-8293856-B2 Process for preparing olefin polymer using mixed catalyst MITSUI CHEMICALS, INC. (JP) 2012-10-23 US disclosed
US-20110077369-A1 PROCESS FOR PREPARING OLEFIN POLYMER USING MIXED CATALYST MITSU CHEMICALS, INC. 2011-03-31 US disclosed