Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.49 |
| ▸ | AURKA | O14965 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31222103 | 0.91 | ALDH1A1 (0.43) | NR3C1AURKALMNAPOLBNPC1 | |
| SCHEMBL31222102 | 0.89 | MEN1 (0.45) | AURKALMNAMEN1CYP1A2MAPT | |
| SCHEMBL31222115 | 0.89 | RAB9A (0.48) | LMNAPOLBNPC1TSHRMEN1 | |
| SCHEMBL31222081 | 0.87 | KCNMA1 (0.40) | POLBNPC1KMT2ASMN1; SMN2AVPR2 | |
| SCHEMBL31222083 | 0.83 | SMN1; SMN2 (0.48) | LMNANPC1MEN1MAPTHTT | |
| SCHEMBL31222075 | 0.83 | KDM1A (0.44) | LMNAPOLBNPC1TSHRMEN1 | |
| SCHEMBL31222071 | 0.81 | GAA (0.43) | LMNANPC1MEN1MAPTKMT2A | |
| SCHEMBL31222119 | 0.81 | GAA (0.39) | AURKALMNANPC1MEN1MAPT | |
| SCHEMBL31222117 | 0.81 | LMNA (0.47) | LMNAPOLBNPC1MEN1CYP1A2 | |
| SCHEMBL31222121 | 0.80 | HSD17B10 (0.39) | AURKALMNAMEN1CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994136-A | Pyrazole compound containing N1-heterocycle, and preparation method and application thereof | 安阳师范学院 | 2024-11-22 | — | — | CN | disclosed |