Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31222102 | 0.90 | MEN1 (0.45) | ALDH1A1KDM4EMAPTLMNAHSD17B10 | |
| SCHEMBL31222075 | 0.89 | KDM1A (0.44) | SMN1; SMN2ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL31222115 | 0.89 | RAB9A (0.48) | SMN1; SMN2ALDH1A1MAPTLMNANPC1 | |
| SCHEMBL31222079 | 0.88 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL31222096 | 0.83 | NR3C1 (0.49) | SMN1; SMN2MAPTLMNANPC1MEN1 | |
| SCHEMBL31222117 | 0.82 | LMNA (0.47) | SMN1; SMN2ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL31222121 | 0.81 | HSD17B10 (0.39) | SMN1; SMN2ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL31222119 | 0.80 | GAA (0.39) | SMN1; SMN2ALDH1A1MAPTLMNANPC1 | |
| SCHEMBL31222089 | 0.79 | L3MBTL1 (0.47) | SMN1; SMN2ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL31222093 | 0.78 | KDM1A (0.46) | SMN1; SMN2MAPTLMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994136-A | Pyrazole compound containing N1-heterocycle, and preparation method and application thereof | 安阳师范学院 | 2024-11-22 | — | — | CN | disclosed |