SCHEMBL312222

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30933461	0.79	HPGD (0.75)	HPGDKDM4ECYP3A4MEN1KMT2A
	SCHEMBL9080220	0.78	AKR1C3 (0.72)	HPGDKDM4ECYP3A4MEN1KMT2A
	SCHEMBL4650047	0.78	HPGD (1.00)	HPGDKDM4ECYP3A4MEN1KMT2A
	SCHEMBL312255	0.77	AKR1C3 (1.00)	HPGDKDM4ECYP3A4MEN1KMT2A
	SCHEMBL1772778	0.77	HPGD (0.78)	HPGDKDM4ECYP3A4MEN1KMT2A
	SCHEMBL15676335	0.75	HPGD (0.74)	HPGDKDM4ECYP3A4MEN1KMT2A
	SCHEMBL21704894	0.75	HPGD (0.74)	HPGDKDM4ECYP3A4MEN1KMT2A
	SCHEMBL312401	0.75	KDM4E (0.59)	HPGDKDM4ECYP3A4MEN1KMT2A
	SCHEMBL311714	0.74	HPGD (0.76)	HPGDKDM4ECYP3A4MEN1KMT2A
	SCHEMBL311588	0.74	HPGD (0.76)	HPGDKDM4ECYP3A4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.